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Procalcitonin as a Prognosis Marker for the Severe Sepsis and Septic Shock Patients in Emergency Department
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Seung Woon Choi, Hoon Kim, Kyung Hwan Kim, Dong Wun Shin, Jun Seok Park, Jun Young Roh, Jun Min Park
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Korean J Crit Care Med. 2011;26(4):250-255.
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DOI: https://doi.org/10.4266/kjccm.2011.26.4.250
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 Abstract
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- BACKGROUND
Advance in sepsis management has increased the survival of patients with sepsis. However, severe sepsis and septic shock patients still have high mortality. We intend to verify the use of the procalcitonin (PCT) level as a prognosis marker in patients with severe sepsis or septic shock in the emergency department (ED).
METHODS
ED Patients with severe sepsis or septic shock were enrolled in our study. We used mortality and Intensive Care Unit (ICU) days as a prognosis index, and compared the PCT level in survivors and non-survivors. We introduced the simplified acute physiology score 3(SAPS3) to assess the severity of the patients and analyzed whether or not the PCT level correlated with the severity index.
RESULTS
The PCT level in septic shock patients [7.36 (0.92-33.69, IQR)] was higher than that in severe sepsis patients [3.24 (0.36-10.53, IQR)] (p = 0.04). However, there was no significant PCT level difference between survivors [median (IQR), 6.59 (0.60-29.25)] and non-survivors [median (IQR), 3.49 (0.40-20.41)] (p = 0.293). The SAPS3 score was higher in the non-survivor group [median (IQR), 64 (59.0-71.5)] than in the survivor group [median (IQR), 77 (68.5-82.0)] (p = 0.001). The PCT level did not correlate with either ICU days or hospital days.
CONCLUSIONS
Using the PCT level as a prognosis factor in severe sepsis and septic shock patients in ED has little value.
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Citations
Citations to this article as recorded by  - Procalcitonin as a prognostic marker for sepsis: a prospective observational study
Saransh Jain, Sanjeev Sinha, Surendra K Sharma, J C Samantaray, Praveen Aggrawal, Naval Kishore Vikram, Ashutosh Biswas, Seema Sood, Manish Goel, Madhuchhanda Das, Sreenivas Vishnubhatla, Nawaid Khan
BMC Research Notes.2014;[Epub] CrossRef
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Diffusion-weighted Imaging of a Patient in a Hypoglycemic Coma: A Case Report
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Kwang Wook Jo, Hoon Kim
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Korean J Crit Care Med. 2010;25(1):30-32.
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DOI: https://doi.org/10.4266/kjccm.2010.25.1.30
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2,377
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- A 65-year-old woman with type 2 diabetes mellitus was found in an unresponsive state and she was admitted to our hospital. She was comatose on arrival. The bedside blood glucose level on admission was 15 mg/dl (normal range, 55-110 mg/dl). After emergency infusion with 50% dextrose, the blood glucose level rapidly normalized to 98 mg/dl, but there was no clinical improvement of her consciousness.
Three days after admission, diffusion-weighted magnetic resonance imaging of the brain revealed bilateral temporal, occipital and frontal lobes lesions with high signal intensity. The patient's neurological condition did not change over the next 15 days. She died of pneumonia on the 30th day of hospitalization. DWI may be useful for detecting and making the differential diagnosis of hypoglycemic coma.
Further, marked differences in the neuroimaging patterns of patients in a hypoglycemic coma are valuable prognostic predictors. We report here on a case of hypoglycemic coma with a poor outcome.
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Citations
Citations to this article as recorded by - Consideration of Prognostic Factors in Hypoglycemic Encephalopathy
Ik-Kwon Seo, Woo-Ik Choi, Sang-Chan Jin, Hyuk-Won Chang
Korean Journal of Critical Care Medicine.2012; 27(4): 209. CrossRef
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